Office: Larkin Hall, rm BO-3
Office Hours: Mon/Wed 9:30 - 10:30 PM or by appointment
Phone: x3630
E-mail: rdavis@murray.fordham.edu

CLASSROOM: Keating Hall 318

• The general objective of the course is to provide a one semester overview of the fundamentals of biochemistry and molecular biology. Emphasis will be on protein structure and function, enzyme catalysis, an overview of energy metabolism, and the maintenance and expression of genetic information.

• Students are required to have had general chemistry, at least one semester of organic chemistry, and introductory biology. At least one additional course in microbiology or genetics will be useful, but is not required.

• Lectures by the instructor, text readings, and supplementary instruction through the internet.

• Grading will be based on 4 exams. Each exam will constitute 25% of the final grade. The fourth exam will be in the final exam period but is not a cummulative final exam. There will be no make-up exams.

• The exam format will be a combination of multiple choice, short answers, and problems.

• Exams will be predominantly based on lecture material. Lectures notes are provided at the course WWW site.

• Rote learning as well as the integrated use and synthesis of information will be required on the exams.

• You are expected to read the lecture notes prior to the class period and have them with you during class to reduce note taking. The WWW notes are not a substitute for taking notes during class. You should note the emphasis of the lectures and take supplementary notes for yourself during class.

• Lectures should be reinforced and clarified by reading the biochemistry text and other outside sources (internet, review guides, study guides, etc.).

• You may find another Biochemistry text or review guide very useful in the course.  Although Stryer is an excellent text, the same topics are also covered in other Biochemistry books and study guides. You may find the style or presentation of another text or review guide more suitable for your study habits. Thus, for some students an outside study guide of some type is highly recommended. Several Other biochemistry texts and reviews guides are listed below.  A number of them are on Reserve at the Science Desk in Walsh Library.

• You should expect to spend a total of ~9 hours/week (~3 hr for each 1 hour of lecture) outside of class going over lecture notes, reading, and exploring the WWW supplementary information and tutorials.

• Additional information to help you is at the Biochemistry 3521 WWW Site including:
• The Lecture Schedule
• Lecture Support: Notes, Readings, WWW Tutorials, etc. for each exam
• Exam I Lecture List
• Exam II Lecture List
• Exam III Lecture List
• Exam IV Lecture List
• Walsh Science Library Reserve List
• 1998 Exams/Keys
• Computer Information and Molecular Graphics for Protein and Nucleic Acid Structure
• Supplementary Book and Study Aids: Printed and Internet
• Internet Tutorials on Topics coverved in the course
• Molecular graphics Aids and Tutorials
• Supplemental information
• A List of other Biochemistry WWW Sites for
• Biochemistry Textbook Supplements on the WWW
• Other Biochemistry Course Notes, Homework and Exams
• Biochemistry and Molecular Graphics Tutorials
• Other Resources
• Netscape Navigator/Internet Tutorial Page
• Simple Netscape Navigator Tutorials
• Internet Tutorials
• Other WWW Resources for Biology, Biochemistry, Molecular Biology
• Netscape Navigator Online Hanbook

• Since the course lecture notes, tutorials, suggested study questions, old exams, and other resources will be at the course World Wide Web site, it is critical that students make an effort to become familiar with using Netscape Navigator WWW browser and the Biochemistry Course Web Site early in the course.

• I strongly recommend that you use the computers in Lab A (Macintosh) or Lab B (PC) in Walsh Library Electronic Information Center to access the course World Wide Web Site to print the lecture notes and particularly for the molecular graphics in the notes and tutorials. Computers in the Walsh Library Electonic Media Center Labs are to be configured for the molecular graphics programs by library personnel.

• Supplementary Guide Available for Stryer: Gumport et al. 1995. Student Companion for Stryer's Biochemistry. 4th edition, W.H. Freeman and Company (Walsh Library Science Reserve)

• Gilbert. 1992. Basic Concepts In Biochemistry, A Student's Survival Guide, McGraw-Hill.
• Available in the Fordham Bookstore andWalsh Library Science Reserve
• Jemiolo, D.K. 1996. Study guide and problems book for Garret and Grisham "Biochemistry". Saunders.Walsh Library Science Reserve
• Campbell and Smith. 1993. Biochemistry Illustrated, Churchill Livingstone. Walsh Library Science Reserve
• Segel, I.H. 1976. Biochemical Calculations. 2nd Edition. John Wiley & Sons.Walsh Library Science Reserve
• Lyman. 1994. Biochemistry, Springhouse Corporation (Applied Science Review).

• Horton et al. 1996. Principles of Biochemistry, 2nd Ed., Prentice-Hall, Inc. Walsh Library Science Reserve.
• Garrett and Grisham. 1995. Biochemistry, Saunders College Publishing. Walsh Library Science Reserve
• Matthews et al. 1997. Biochemistry: A short course. John Wiley & Sons.Walsh Library Science Reserve
• Zubay. 1993. Biochemistry, Wm. C. Brown Communications. Walsh Library Science Reserve
• Voet and Voet. 1990. Biochemistry, . Publisher Walsh Library Science Reserve
• Hames et al. 1997. Instant Notes in Biochemistry. Bios Scientific Publishers.
• Lehninger, Nelson and Cox. 1993. Biochemistry, 2nd Ed., Publisher.
• Ritter. 1996. Biochemistry: A foundation, Brooks/Cole Publishing Co

• Turner et al. 1997. Instant Notes in Molecular Biology. Bios Scientific Publishers.
• "Genes VI", B. Lewin. 1996. Oxford University Press. Walsh Library Science Reserve
• "Molecular and Cell Biology", H. Lodish et al. 1995. 2nd edition, W.H. Freeman and Company. Walsh Library Science Reserve
• Alberts et al. 1997. Essential Cell Biology. Garland Publishing. Walsh Library Science Reserve
• "Genes and Genomes: A Changing Perspective", M. Singer and P. Berg, 1991. Univ. Science Books
• "Molecular Biology of the Gene", J.D. Watson et al. 1987. 4th edition, Benjamin Cummings
• "Molecular Biology of the Cell", B. Alberts et al. 1994. 2nd edition, Garland Publishing
• "Essentials of Molecular Biology", D. Freifelder and Malacinski, 1993. Jones and Bartlett
• "Molecular Biology", D. Freifelder, 1987. 2nd edition, Jones and Bartlett

• Micklos, D.A. and Freyer, G.A. 1990. DNA Science: A first course in recombinant DNA technology. Cold Spring Harbor Press. Walsh Library Science Reserve
• Watson, J.D. et al. 1992. Recombinant DNA. Scientific American Books, W.H. Freeman and Company. Walsh Library Science Reserve
• Old, R.W. and Primrose, S.B. 1994. Principles of Gene Manipulation: An introduction to genetic engineering. Blackwell Scientific Publications. Walsh Library Science Reserve

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