Pathway for the movement of acetyl-CoA units from within the mitochondrion to the cytoplasm for use in lipid and cholesterol biosynthesis. Note that the cytoplasmic malic enzyme catalyzed reaction generates NADPH which can be used for reductive biosynthetic reactions such as those of fatty acid and cholesterol synthesis.

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Michael W. King, Ph.D / Medical Biochemistry / Terre Haute Center for Medical Education / memwk@thcme.indstate.edu
Last modified:   Wednesday, 12-Apr-00 15:22:07